Health Risks in Cambodia: a guide to staying safe

Like any country in Southeast Asia, Cambodia comes with specific health risks that are important to understand in order to stay safe and enjoy your time here.

This guide gives you a practical and medical overview to help you navigate daily life or travel in Cambodia with confidence.

1. Mosquito-borne diseases

Mosquitoes are responsible for most infectious health risks in Cambodia. Dengue fever is very common.

FeatureDengueMalariaChikungunyaZika
Current status in CambodiaEndemic with seasonal outbreaks (rainy season).Cases have sharply declined; elimination targeted by 2025 but persists in forested/remote areas.Sporadic outbreaks, most recently in the 2010s and 2020s.Sporadic, low-level detection with no major outbreaks.
Causative agentDengue virus (DENV 1–4).Plasmodium spp. (P. falciparum, P. vivax).Chikungunya virus.Zika virus.
Main vectorsAedes aegypti and Aedes albopictus.Anopheles mosquitoes, especially in forested regions.Aedes aegypti and Aedes albopictus.Aedes aegypti and Aedes albopictus.
Common symptomsHigh fever, severe body pain, rash; risk of severe dengue.Fever, chills, headache, fatigue, anemia.High fever, severe joint pain, rash, fatigue.Mild fever, rash, conjunctivitis, joint pain; often asymptomatic.
High-risk areasNationwide during rainy season; higher in densely populated provinces.Northeast and forested areas (Ratanakiri, Mondulkiri, Pursat).Can occur nationwide; higher where Aedes mosquitoes are common.Sporadic cases mostly in urban areas.
TreatmentSupportive care.Antimalarial drugs.Supportive care.Supportive care.
PreventionMosquito control, eliminating breeding sites, personal protection; dengue vaccine (Qdenga) available at IntercareBed nets, repellents, antimalarial prophylaxis for at-risk groups (available at Intercare)Mosquito control, personal protection.Mosquito control, personal protection; pregnancy-related precautions.

Dengue Fever

  • Very common, especially during the rainy season.
  • Symptoms: high fever, intense fatigue, joint pain, headache.

Malaria

Malaria in Cambodia has declined significantly over the past decade, largely due to aggressive surveillance, widespread use of insecticide-treated nets, and improved access to rapid diagnostics and treatment. The country has eliminated Plasmodium falciparum malaria in several provinces and is aiming for full malaria elimination by 2025.

However, challenges remain in remote forested areas, where mobile and migrant populations face higher risk and drug-resistant strains have historically emerged.

Chikungunya

Chikungunya has periodically resurfaced in Cambodia, with outbreaks driven by Aedes mosquitoes in both urban and rural areas. While most cases cause fever and joint pain, control efforts focus on mosquito reduction and community awareness to limit transmission.

Zika

Zika virus has been detected sporadically in Cambodia, with low-level transmission linked to Aedes mosquitoes similar to those that spread dengue and chikungunya. Surveillance remains in place to monitor potential outbreaks, especially because infections can be asymptomatic and pose risks during pregnancy.

How to prevent it:

  • Use repellent containing DEET or picaridin.
  • Wear long sleeves and trousers in the evening.
  • Sleep under a mosquito net in rural areas.
  • Remove any standing water around your home.

2. Food-borne illnesses and digestive infections

Heat and occasional lack of food hygiene = a high risk of gastrointestinal problems.

Common issues include:


FeatureTraveler’s DiarrheaSalmonella InfectionParasitic InfectionsFood/Water-Borne Food Poisoning (ice, raw vegetables, unclean water)
CauseUsually bacterial (E. coli, Campylobacter), sometimes viral or parasiticSalmonella bacteriaProtozoa (e.g., Giardia, Entamoeba histolytica) or helminthsBacterial contamination, toxins, or exposure to unclean water/ice or raw produce
How it’s commonly contracted in CambodiaEating contaminated street food, unrefrigerated food, or unsafe waterUndercooked poultry, eggs, meat; contaminated produceContaminated water, unwashed fruits/vegetables, poor hygieneIce made from untreated water, raw salads, unpeeled fruits, dirty food handling
Main symptomsSudden diarrhea, cramps, nausea, fatigueFever, diarrhea (sometimes bloody), abdominal crampsPersistent diarrhea, bloating, stomach pain, sometimes prolonged symptomsNausea, vomiting, diarrhea, stomach pain within hours of eating
Onset1–3 days after exposure6–72 hoursDays to weeks after exposureMinutes to hours depending on toxin
SeverityUsually mild to moderate; resolves in a few daysMild to severe; can cause dehydrationCan become chronic if untreatedUsually short-term but can be intense
TreatmentHydration, oral rehydration salts (ORS), rest; antibiotics only for severe casesHydration; antibiotics for confirmed moderate/severe casesDepends on parasite: antiparasitic medication (e.g., metronidazole, albendazole)Hydration, rest; symptoms usually self-limiting
Prevention in CambodiaEat hot, freshly cooked food; avoid unsafe waterAvoid undercooked meats/eggs; ensure proper hygieneDrink safe water; wash/peel fruits; avoid raw saladsAvoid ice unless from purified water; avoid raw veggies; choose reputable eateries
Higher-risk situationsStreet food stalls with poor hygieneStreet food, buffets, undercooked market foodsRural visits, untreated water sourcesSmall eateries using untreated water for washing or ice

How to prevent it:

  • Drink only bottled water with an intact seal.
  • Avoid ice in small restaurants.
  • Avoid unpeeled fruit and raw vegetables from street stalls.
  • Wash hands frequently or use hand sanitizer.
Food poisoning prevention

Doctor’s tip:
When diarrhea occurs, rehydration comes first. Antibiotics are only necessary in specific situations.

3. Heatstroke and dehydration

Cambodia can reach 40°C (104°F) with very high humidity. Dehydration is extremely common, especially among:

  • children,
  • new arrivals,
  • anyone active outdoors.

Warning signs: headaches, dizziness, fatigue, muscle cramps.

Heat stroke

How to prevent it:

  • Drink regularly: don’t wait until you feel thirsty.
  • Avoid direct sun between 11 a.m. and 3 p.m.
  • Wear a hat and lightweight clothes.

If dehydration is too important, you can prepare an ORS (Oral Rehydration Solution):

4. Air pollution and allergies

Phnom Penh and some rural areas experience episodes of air pollution, particularly during agricultural burning.

Risks:

  • Respiratory irritation
  • Asthma attacks
  • Allergies and conjunctivitis

How to prevent it:

  • Monitor the AQI (Air Quality Index) through AirVisual (free application).
  • Wear a protective mask (FFP2/N95) on high-pollution days.
  • Use an air purifier at home, especially if you have children.

5. Rabies: a real concern

Cambodia has one of the highest rabies rates in Asia. Stray dogs are common, and cats or monkeys can also transmit the disease.

Rabbies vaccination

How to prevent it:

  • Avoid touching stray animals (dogs, monkeys, bats, …).
  • Pre-exposure vaccination (available at Intercare) is recommended for:
    – expatriates,
    – children (40% of the victimes are children younger than 15),
    – people living in rural areas.

The vaccination protocole has been updates in 2019: 3 injections day 0, day 3 and day 7.

Source: A 1-week intradermal dose-sparing regimen for rabies post-exposure prophylaxis (RESIST-2): an observational cohort study, The Lancet Infectious Diseases, 26 septembre 2019.

If you get bitten:

  • Wash the wound immediately with soap and water for 15 minutes.
  • Seek medical care urgently for post-exposure vaccination: immunoglobulin, vaccination in emergency (as soon as possible, < 24h after the exposure)
  • Never ignore even a small bite.

6. Environmental hazards: wounds, infections, and bites

The tropical climate increases the risk of skin problems such as:

  • infections
  • abscesses
  • infected insect bites

Prevention:

  • Clean even the smallest wounds thoroughly.
  • Keep your feet dry (foot infections are common).
  • Wear closed shoes during hikes or jungle trips.

7. Sun exposure: burns and premature aging

The sun in Cambodia is strong, even when it’s cloudy.

How to protect yourself:

  • Use SPF 50+ sunscreen and reapply every two hours.
Use always SPF 50+
  • Wear UV-filtering sunglasses.
  • Keep children out of the sun between 11 a.m. and 4 p.m.

Conclusion

Being aware of the main health risks allows you to:

  • protect yourself and your family,
  • avoid unnecessary problems,
  • enjoy your life or travels here with peace of mind.
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